What is Ginkgo Standardized Extract?
Ginkgo Standardized Extract is a high-quality, botanical ingredient that is extracted and standardized from the leaves of Ginkgo biloba with a controlled process to provide consistent quality and standardized active levels of naturally-occurring compounds. The extract is generally sold as a fine brownish-yellow powder and is used in various industries such as dietary supplements, functional food, beverages, and botanical formulation. It has a fixed composition, which simplifies production scale-up, quality control, and formulation. It is extracted, purified, concentrated, and analysed multiple times to ensure it conforms to the set specifications within the strict quality management system. Commonly used advanced analytical techniques include identity, purity, active constituent, microbiological, and heavy metal testing. This all-encompassing quality control system helps the ingredient conform to the needs of international markets and professional uses in production. Its formulation versatility and compatibility with various finished product types such as capsules, tablets, powders, sachets, gummies, and functional beverage formulations make it an excellent value for product development. It is controlled in particle size and composition and is easily handled, making it suitable for a variety of processing technologies and production systems.

COA
| Item | Specification | Result | Test Method |
| Product Name | Ginkgo Standardized Extract | Ginkgo Standardized Extract | Internal Method |
| Botanical Source | Ginkgo biloba L. Leaf | Conforms | Visual |
| Part Used | Leaf | Conforms | Visual |
| Appearance | Fine Brownish Yellow Powder | Fine Brownish Yellow Powder | Visual |
| Identification | Positive | Positive | TLC |
| Assay (Flavone Glycosides) | ≥24.0% | 24.68% | HPLC |
| Assay (Terpene Lactones) | ≥6.0% | 6.21% | HPLC |
| Ginkgolic Acids | ≤5 ppm | 2.3 ppm | HPLC |
| Particle Size | 100% Pass 80 Mesh | Conforms | USP <786> |
| Loss on Drying | ≤5.0% | 3.12% | USP <731> |
| Ash Content | ≤5.0% | 2.46% | USP <281> |
| Bulk Density | 0.40–0.70 g/ml | 0.56 g/ml | USP Method |
| Tapped Density | 0.50–0.90 g/ml | 0.72 g/ml | USP Method |
| Residue on Solvents | Meets USP Requirements | Conforms | USP <467> |
| Lead (Pb) | ≤2.0 ppm | 0.18 ppm | ICP-MS |
| Arsenic (As) | ≤1.0 ppm | 0.09 ppm | ICP-MS |
| Cadmium (Cd) | ≤1.0 ppm | 0.05 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | 0.02 ppm | ICP-MS |
| Total Plate Count | ≤10,000 CFU/g | 380 CFU/g | USP <2021> |
| Yeast & Mold | ≤1,000 CFU/g | 45 CFU/g | USP <2021> |
| E. coli | Negative | Negative | USP <2022> |
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Side Effects
Ginkgo Biloba Extract is generally safe for use in formulated products, but like most concentrated herbal extracts, it may cause mild and temporary effects in some people based on dosage, formulation, and/or their personal dietary habits and dietary intake, depending on dose level. Side effects may include mild sensitivity of the skin in sensitive skin types, nausea, headache, dizziness, stomach discomfort, and irritation reported on occasion. Oral doses higher than those recommended in the formulations might result in an increased risk of unintended side effects. Product developers need to make sure that they specify, test quality, and label products in an appropriate way to facilitate responsible product use. Standardization of the level of active constituent, reduction of impurities, and compliance with quality standards are crucial for manufacturers who wish to provide the final product with a consistent ingredient profile and reduce product variability. Any botanical raw material, such as this one, should be evaluated for safety, regulatory compliance, and formulation prior to commercial use, based on requirements of the target market.
Ingredient Combinations
Commercial supplement and functional nutrition product development often involves the incorporation of multiple botanical extracts, vitamins, minerals, amino acids, and specialty nutrients for expanding the nutrition market. It can be formulated with many other ingredients, depending on the desired positioning of the product and the targeted customer group, such as phosphatidylserine, lutein and zeaxanthin, grape seed extract, green tea extract, bacopa extract, Rhodiola rosea extract, coenzyme Q10, alpha lipoic acid, and B-complex vitamins. It can also be used in botanical blend capsules, powdered functional beverages, gummies, stick packs, and tablet formulations in which plants are desired. Ginkgo Leaf Extract also provides good compatibility with both water-dispersible and powder-based ingredients, giving product developers a chance to develop a unique combination of ingredients and to ensure manufacturing efficiency and ingredient stability. The individual pairing of ingredients is usually dictated by the market trends, product format needs, labeling goals, and the general concept of the formulation defined by the brand owner or contract manufacturer.

Formulation Reference
|
Ingredient |
Specification |
Amount (mg/Serving) |
|
Ginkgo Biloba Leaf Extract |
24% Flavone Glycosides, 6% Terpene Lactones |
120 mg |
|
Phosphatidylserine |
50% PS |
100 mg |
|
Bacopa Monnieri Extract |
20% Bacosides |
150 mg |
|
Lutein |
10% HPLC |
20 mg |
|
Zeaxanthin |
5% HPLC |
4 mg |
|
Coenzyme Q10 |
98% HPLC |
50 mg |
|
Vitamin B6 |
USP Grade |
2 mg |
|
Vitamin B12 |
1% Grade |
0.5 mg |
Disclaimer
This formulation is only given as a reference for product development, research, and evaluation. The ingredient combination and specification and how it is used are illustrative and may not be considered as serving sizes, efficacy, or guidance for regulatory purposes. Manufacturers aim to carry out formulation evaluation, stability testing, safety evaluation, label review, and/or regulatory compliance verification on their own, as per the needs and requirements of the target market. The composition of the product may need to be modified based on the local regulations, intended product positioning, processing conditions, and customer specifications.
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