What is Giant Knotweed Root Extract?
Giant Knotweed Root Extract is a standardized botanical extract of the rhizome of Reynoutria sachalinensis (also known as giant knotweed), processed by controlled extraction and purification processes to extract naturally occurring polyphenols, such as resveratrol and others. This extract is marketed as a standardized plant-based raw material with a uniform set of specifications, usually provided in a specified assay range (e.g., resveratrol content as HPLC), with stable physicochemical characteristics and with a wide range of different formulation systems. Manufacturers widely use it in dietary supplements, functional foods, cosmetics, and nutraceutical supply chains because of its plant source, traceability of sourcing, and scale in large quantities. It has found application in the industrial sector as a botanical active that may be used to add to products that are antioxidant-focused product positioning and clean-label formulations, while considering the global regulatory and quality standards. The ingredient is commonly available in the form of an excellent flowing fine powder with good solubility and flowability properties, which enable its incorporation into capsules, tablets, beverages, or topical systems.

COA
| Item | Specification | Result | Method |
| Appearance | Fine powder | Complies | Visual |
| Color | Light brown to off-white | Complies | Visual |
| Odor | Characteristic | Complies | Organoleptic |
| Taste | Slightly bitter | Complies | Organoleptic |
| Particle Size | 95% pass through 80 mesh | Complies | Sieve Analysis |
| Bulk Density | 0.40–0.65 g/mL | 0.52 g/mL | USP Method |
| Trans-Resveratrol | ≥ 50.0% | 50.82% | HPLC |
| Polydatin | ≥ 5.0% | 5.37% | HPLC |
| Loss on Drying | ≤ 5.0% | 3.21% | USP <731> |
| Ash | ≤ 2.0% | 1.18% | USP <281> |
| Lead (Pb) | ≤ 2.0 ppm | < 1.0 ppm | ICP-MS |
| Arsenic (As) | ≤ 1.0 ppm | < 0.5 ppm | ICP-MS |
| Cadmium (Cd) | ≤ 1.0 ppm | < 0.2 ppm | ICP-MS |
| Mercury (Hg) | ≤ 0.1 ppm | < 0.05 ppm | ICP-MS |
| Residual Ethanol | ≤ 5000 ppm | 1320 ppm | GC |
| Total Plate Count | ≤ 1,000 CFU/g | < 200 CFU/g | USP <2021> |
| Yeast & Mold | ≤ 100 CFU/g | < 50 CFU/g | USP <2021> |
| Escherichia coli | Negative | Negative | USP <2022> |
| Salmonella | Negative | Negative | USP <2022> |
| Staphylococcus aureus | Negative | Negative | USP <2022> |
| Solubility | Partially soluble in ethanol | Complies | Internal Method |
Where to buy Giant Knotweed Root Extract?
Being a professional manufacturer, Kingsci provides controlled specifications, consistent quality, and large quantity supply functions according to the requirements of dietary supplements, functional foodstuffs, and cosmetic industry applications. We are focusing on the standardized extraction processes, quality assurance, and flexible OEM/ODM services to fulfill various formulation needs.
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Main Ingredients
Giant Knotweed Extract comprises various naturally occurring polyphenolic compounds, with trans-resveratrol being the main and most commercially useful active marker since it is relatively high in concentration and can be easily standardized to control its quality. Along with resveratrol, the extract normally contains related stilbenes, like polydatin (resveratrol glucoside), and anthraquinones, like emodin and physcion, and smaller quantities of flavonoid and tannin that are considered to make up the totality of the phytochemical profile. Manufacturing and formulation perspectives: Trans-resveratrol can be considered as the key specification parameter due to its stability behavior, ease of analysis through HPLC, and applicability in product positioning of supplement, food, and cosmetic products. These complementary compounds can perhaps benefit the wider formulation stories concerning the use of such open systems based on plant-derived antioxidants and polyphenol concentration, whilst suppliers concentrate on providing controlled ratios, purity levels, and batch consistency to satisfy the needs relating to the industrial application and regulatory compliance.
Process
1. Raw Material Selection and Pre-treatment
Giant knotweed rhizomes are dried and then inspected and purified to eliminate contaminants. Mechanical crushing or milling is then done to raise the surface area to enhance the extraction efficiency and to ensure uniform penetration of solvent when doing large-scale extraction.
2. Solvent Extraction (Ethanol or Hydroalcoholic System)
Plant material is milled and extracted in food-grade ethanol or water/ethanol mix under controlled temperature conditions. This process solubilizes target polyphenols as well as optimizing yield and selectivity, and is thus the most widespread and scalable process in industry.
3. Solid–Liquid Separation
The mixture is then extracted and filtered or centrifuged to obtain the liquid extract and the plant residue. This is done to give clarity to the extract solution and to concentrate it downstream.
4. Concentration Under Reduced Pressure
Vacuum evaporation is used to concentrate the filtrate to eliminate the excess solvent, but in order to retain heat-sensitive compounds. This action enhances a high concentration of active constituents and a smaller general processing volume.
5. Purification and Enrichment
The concentrated extract can then be further purified (e.g., by resin adsorption/desorption or recrystallization) depending on the desired target specification (e.g., resveratrol percentage). The step improves the composition of major marker compounds and eliminates undesirable impurities.
6. Drying (Spray Drying or Vacuum Drying)
The extract is purified, and it is then sprayed or vacuum-dried to a stable powder form. The addition of carriers might be done when it is necessary to enhance the flowability and stability of the powder to be handled in industry.
7. Milling and Sieving
The dried content is carefully milled and sieved to get a homogeneous particle size to provide uniformity in the formulation processes downstream, such as encapsulation or blending.
8. Quality Control and Standardization
Analytical tests like HPLC are used to test final batches to determine the level of active compounds, solvent residues, heavy metal content, and microbiological parameters. Standardization provides batch-to-batch consistency in accordance with business requirements.
9. Packaging and Storage
Giant Knotweed Rhizome Extract is filled into moisture-proof and food-grade (e.g., fiber drums that are lined with an inner lining) containers and stored under controlled conditions to ensure stability during transport and during the storage time.

Suitable For
To a manufacturer, Knotweed Root Extract would typically be positioned as an ingredient in an end product to target the mass consumer populations that are interested in polyphenol-containing formulations, plant-derived, clean-label ingredients, and consumers interested in antioxidant-based, nutritional-focused, or cosmetic-oriented products in their daily routines. It is widely integrated into the mainstream dietary supplement, functional food, and personal care, where the needs are guided by the interest in botanical sourcing, clear ingredient profiles, and can be used together with vegan or naturally positioned product line needs. Moreover, the ingredient is frequently associated with product ideas targeted at consumers who are interested in a balanced lifestyle, urban consumers with busy schedules, and consumers who prioritize standardized botanical extracts in their overall diets or skincare routines, but leave the positioning to be adapted by the brand owners according to the trends and regulatory systems in the region.
The Best Giant Knotweed Root Extract Supplier
As an industry player with more than 15 years of experience, Kingsci can be regarded as a safe source for its clients worldwide in search of quality products and production quantities. The company is concentrated on the standard manufacturing process, the strict control over the main markers like the resveratrol content, and the strong quality control according to international expectations. Kingsci encourages adaptable OEM/ODM services in which the partners can tailor the specifications, formulations, and packaging according to certain market demands and application contexts. With a strong raw material sourcing base and sophisticated extraction process, together with thorough technical documentation, Kingsci offers an effective and clear-cut supply solution to manufacturers in the dietary supplements, functional foods, and cosmetic industries.
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