Ergothioneine Amino Acid Powder

Ergothioneine Amino Acid Powder is a water-soluble and high-purity ingredient initially intended for the development of state-of-the-art nutritional supplements, as well as in cosmetics and functional food applications. It is a naturally occurring thiol derivative of histidine and can be biosynthesized by some fungi and bacteria; common commercial sources are fermentations of Hericium erinaceus, Pleurotus ostreatus, or Aspergillus species. It has been noted to be unusually tissue-accumulating in tissues subject to oxidative stress and metabolic activity, i.e., liver, kidneys, and skin, because of its specialized transport system (OCTN1). It is usually provided as a fine, free-flowing white to off-white powder, 98% or more purity. It is also stable over a wide pH and thermal conditions, thus highly acceptable in complex formulations. Within the nutraceutical industry, it is commonly positioned as a next-generation cellular health ingredient, where it helps to support mitochondrial functions and oxidative balance. In cosmetics, it is applied in anti-aging and skin-brightening products due to its biocompatibility and synergistic activity with other active compounds.

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Structurally, it is a thiol/thione tautomer of histidine, with a sulfur atom attached to an imidazole ring, providing extreme resistance to oxidation and allowing selective redox activity. It is not easily auto-oxidized (even in the presence of light, heat, and oxygen), which is a problem with many other antioxidants, so it is highly resistant to destruction during processing and storage. Amino Acid Ergothioneine also exhibits a zwitterionic nature at physiological pH, which may add to its outstanding water solubility and bioavailability. Its stability to degradation over a broad pH range (roughly pH 210) and its aqueous and semi-solid compatibility efficacy make it especially well suited to application in oral and topical formulations. Moreover, it displays cell-specific accumulation through the transporter OCTN1, which is not seen with ordinary dietary antioxidants, indicating a possible biological role in cellular redox regulation.

1. Store in a Cool, Dry Environment

Store the product in a temperature-controlled place, preferably at a temperature below 25 o C (77 o F), out of the reach of heat and humidity to avoid absorption of moisture and possible degradation.

2. UV and Direct Sunlight Exposure should be avoided

Even though Ergothioneine Powder is relatively stable, it is not recommended to be exposed to light, particularly direct sunlight or UV, over extended periods to retain maximum quality.

3. Keep in Original Sealed Packaging

We pack the product in air-tight and moisture-resistant packages that are internationally safe and of high quality. To avoid deterioration, the powder ought to be kept in the original, sealed container until needed.

4. Minimize Air Exposure After Opening

When it is necessary to repackage or transfer the product inside the plant, make sure that it is done in dry and low-humidity conditions. Where vacuum sealing or nitrogen flushing is possible, exposure to oxygen should be minimized.

5. Avoid Contact with Reactive Substances

Should not be stored next to strong acids, bases, or oxidizing agents. This is a precaution that aids in maintaining the chemical structure and performance traits of the product.

6. Use Desiccants if Necessary

When retained in containers that are partially used, add desiccant packets and reclose the container tightly to minimize the entry of moisture.

Suppliers generally offer it as a premium health and wellness ingredient in effervescent tablets, liposomal products, functional drinks, and nutraceutical capsules, where cellular health and metabolic vitality are the proposed selling points. It is also a very good choice due to its solubility and thermal stability in liquid and semi-solid matrices utilized in dermaceutical applications (e.g., emulsions, ampoules, and hydrogel-based skincare systems). Within the personal care sector, it is getting more popular in precision-targeted formulation, anti-fatigue and environmental protection claims, mainly in high-end facial serums and eye contour products. Ergothioneine is also getting momentum in food-tech and ingredient development to fortify dairy analogs, sports nutrition formulas, and cognitive support beverages, particularly where clean-label and bioavailable antioxidants are sought. It is most successfully applied in the formulations focusing on cellular health, oxidative balance, and long-term vitality support, which fits the product development target in next-generation health and functional ingredient segments.

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