Product Introduction
Kojic acid is a weak acid compound produced by fermentation. It is small molecular weight, can be directly absorbed through the skin, and has a high utilization rate. It can prevent the generation of tyrosinase, inhibit the generation of melanin, and block the generation of melanin spots.
Kingsci is well-known as one of the leading kojic acid manufacturers and suppliers in China. If you're going to wholesale bulk kojic acid in stock, welcome to get pricelist and quotation from our factory. For price consultation, contact us.
Product Description
|
English name |
Kojic Acid |
|
Specification |
98% |
|
Appearance |
Off white powder |
|
Odor |
Characteristic |
|
CAS NO. |
501-30-4 |
|
Molecular formula |
C6H6O4 |
|
Molecular weight |
142.11 |
|
Water solubility |
Soluble |
Mechanism of Action
Melanin is synthesized by melanocytes at the lower layer of epidermis. Melanocytes are classified in the category of specialized dendritic cells that are located among epidermal keratinocytes and they play the primary role of melanin production within an organelle called melanosomes, and thus spread to surrounding keratinocytes. Each melanocyte makes contact with melanosomes in different stages of the dendritic cells and is distributed in many keratinocytes. Melanins are complex polymers that are derived from tyrosine and other intermediates. Tyrosinase contains copper ions in the active site. When exposed to UV rays, the copper ion commands the tyrosinase to become more active. Kojic Acid captures the copper ion, preventing that from activating the tyrosinase. By inhibiting the activities of tyrosinase, Kojic Acid can also prevent creating melanin.
Safety of kojic acid
If the concentration is controlled within 1%, it has little irritation to the eyes and skin.
Although there may be very few transient slight skin irritation, slight skin allergy and slight light sensitivity, there is no problem with safety
Tips:
1. Kojic acid is unstable to light, heat and metal ions. Do not add it at high temperature during formulation. Control the content of iron and other metal ions in the system.
2. It is better to add appropriate complexing agents such as EDTA and antioxidants such as sodium sulfite in the system.
3. Recommended dosage: 0.5 ~ 1.0%.
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