About Natural Salicin You Have To Know

Apr 25, 2022 Leave a message

In this article about natural Salicin you have to know

Product name: Salicin

Plant source: White Willow Bark Extract

Molecular formula: C13H18O7

Molecular weight: 286.28

Specific rotation: -61.5 º (C=5, WATER)

Water soluble: 36 G/L (15 ºC), 250 G/L (60ºC)

 

Salicin Overview

Salicin is a white crystal with a bitter taste; the melting point is 199~202℃; soluble in water, easily soluble in boiling water, insoluble in ethanol (1:90), insoluble in ether or chloroform, but soluble in alkaline solution, pyridine or glacial acetic acid. Its aqueous solution is neutral, and there is no free phenolic hydroxyl group in the molecule, which belongs to phenolic glycosides. Glucose and salicylic alcohol can be generated by enzymatic hydrolysis of dilute acid or bitter almonds.

 

KS Salicin Specification

15% brownish yellow, high ash content, average water solubility

25% brownish yellow, high ash content, average water solubility

30% yellow, high ash content, good water solubility

50% light yellow, high ash content, good water solubility

80% off-white, low ash content, good water solubility

98% white, low ash, good water solubility

 

Salicin Benefits

1. It is used to treat mild fever, cold, infection (influenza), acute and chronic rheumatic discomfort, headache and pain due to inflammation. Aspirin (acetylsalicylic acid), a synthetic substitute for salicin, has potentially dangerous gastrointestinal side effects. In its natural form, salicin passes harmlessly through the gastrointestinal system and is converted to salicylic acid in the blood and liver. The conversion process takes hours, so the results are not immediately felt by the body, but the general effect lasts for a few hours.

 

2. Relieve Arthritis Pain and Low Back Pain

Salicin is thought to be the source of white willow bark's anti-inflammatory and pain-relieving abilities. White willow bark's pain-relieving power is generally slower to act but lasts longer than regular aspirin products. One trial found that a product of a herbal compound containing 100 ng of salicin was effective in improving pain relief in people with arthritis after two months of continuous administration.

 

Another trial found that a daily intake of 1360mg of white willow bark extract (containing 240mg of salicin) for two weeks was more effective in the treatment of joint pain and/or arthritis. Using high-dose white willow bark extract may also help relieve low back pain. A four-week trial found that white willow bark extract containing 240 mg of salicin was effective in reducing the exacerbation of low back pain.

 

3. It can soften keratin, make it fall off, enhance skin smoothness, etc.

* Acne and acne: soften and fall off the keratin, reduce pore blockage, and have a good effect on puberty acne and acne vulgaris.

* Blackheads and keratinization of the hair circumference: It can soften and remove the top of the blackheads and keratin, so that the skin smoothness can be temporarily improved.

* Through keratin exfoliation, remove excess keratin around the hair, relieve keratinization around the hair, and have a poor effect on organic large pores.

* For medical purposes, a high concentration solution exfoliates the epidermis in a short period of time for the treatment of moderate to severe acne, ichthyosis, etc.

* Whitening: Accelerates the exfoliation of the stratum corneum, so that the melanin in the keratinocytes is exfoliated together, revealing a lighter complexion.

* Soften the skin: The stratum corneum is thinned and the skin feels softer.

 

Salicylic acid has certain irritation and side effects and is a restricted substance in cosmetics. The content in ordinary cosmetics should not exceed 2%, and in washing, products should not exceed 3%.

 

KS Corporate Standard

Appearance: yellow-brown powder

 

Identify

TLC: TLC examination, the spots are obvious;

UV: HPLC inspection, salicin content meets the requirements.

 

Test standard

①Loss on drying: ≤5% (test method of Chinese Pharmacopoeia 2015 edition);

②Ash content: ≤10% (test method of Chinese Pharmacopoeia 2015 edition);

③Heavy metals: ≤10ppm (test method of Chinese Pharmacopoeia 2015 edition);

④Pesticide residues: ≤1ppm (test method of Chinese Pharmacopoeia 2015 edition);

⑤Particle size: 100% pass 80 mesh

⑥Packing: Double-layer plastic bags are sealed, and the outer barrel is printed with the product name, gross weight, batch number, production unit, production time, effective time, storage and transportation methods, etc.

 

Colony standard

①Total number of bacteria≤NMT1,0000cfu/g

②Total number of molds≤NMT1000cfu/g

③Escherichia coli: meet the requirements

④Salmonella: meet the requirements

 

Specifications: 15%, 25%, 30%, 50%, 80%, 98%

Storage: Cool, dry, dark.