What is Fisetin? Fisetin is an antioxidant found in fruits and vegetables, including strawberries, apples, and cucumbers. According to research published in Frontiers in Chemistry, flavonoids show "potential as anti-inflammatory, chemopreventive, chemotherapeutic and aging drugs." It has received a lot of attention for its anti-aging properties. Recent studies have shown that this antioxidant has potent anti-aging activity, preventing the replication of damaged DNA. This means fisetin supports healthy aging and fights chronic disease.
What is the best source of fisetin?
Fisetin powder is a yellow plant pigment and chemical that occurs naturally in foods, especially fruits and vegetables. The following foods contain fisetin
Strawberry
Apple
persimmon
Grape
Onion
Cucumber
Kiwi
Kale
Peach
Lotus root
Mango
Fisetin benefits
1. Used as an antioxidant
Studies have shown that bulk fisetin has the ability to scavenge free radicals with significant biological effects. These oxygen free radicals damage lipids, amino acids, carbohydrates, and nucleic acids. When we don't eat enough antioxidant foods, an imbalance of oxygen species occurs that inhibits the body's ability to defend itself.
2. Has anti-aging activity
Research published in The Lancet shows that fisetin powder, a flavonoid, has potent anti-aging activity in both mouse and human tissues. This means that antioxidants can prevent the replication of damaged DNA, which may play a role in aging and age-related diseases. When the researchers tested 10 flavonoids, including resveratrol, rutin, luteolin, curcumin and fisetin, they found that fisetin was the most effective anti-aging drug.
3. Has anti-cancer properties
The data suggest that fisetin bulk has anti-proliferative properties in several cancers, meaning it inhibits tumor cell growth, with potential value in cancer prevention and treatment as it reduces angiogenesis and inhibits tumor growth.
4. Reduce inflammation
According to research published in Advances in Experimental Medicine and Biology, fisetin has been shown to have potent anti-inflammatory effects in cell cultures and in animal models relevant to human disease.
5. Promoting Healthy Ageing
Because fisetin powder is an anti-aging drug, it can prolong your health and longevity. Studies have shown that it promotes healthy aging by reducing oxidative stress and increasing glutathione levels. It also reduces the production of pro-inflammatory molecules and activates key neurotrophic factor signaling pathways that support growth, survival and healthy aging.
6. Promotes Heart Health
Research shows that fisetin can help promote cardiovascular health in a number of ways. Antioxidants can induce heart regeneration by activating genes involved in cell proliferation, one analysis reported. Researchers believe it can prevent ischemic damage after a heart attack. There is some evidence that fisetin may also help prevent stroke. One animal study found that fisetin, quercetin, and aspirin significantly prolonged clotting time and thrombin time.
Fisetin dosage
The amount of fisetin consumed in clinical trials varied widely, with participants taking doses ranging from 100 mg per day to 1,400 mg per day. Fisetin supplement label recommendations also vary, with dosages ranging from 100-500 mg per day. There aren't enough studies to make an educated recommendation about an appropriate fisetin dose.
Fisetin side effects
The safety of high-dose fisetin bulk powder is relatively unknown. Many studies involve cell cultures or animal tissue, while a few involve human tissue. The safest way to boost your health with antioxidants is to eat fresh fruits and vegetables.
In conclusion, Fisetin powder is a plant pigment and antioxidant that has received much attention for its anti-aging properties. Flavonoids are known for their ability to prevent damaged DNA replication, thereby reducing the risk of aging, degenerative diseases, heart disease and cancer. It is found in fruits and vegetables such as strawberries, cucumbers, apples and onions, and should be supplemented with these foods in daily life.
Related articles
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842927/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689181/
https://www.thelancet.com/article/S2352-3964(18)30373-6/fulltext
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689181/
https://pubmed.ncbi.nlm.nih.gov/27671819/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527824/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031222/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132235/
