1. What is NAD+?
NAD+ is an essential coenzyme in the redox process and the only substance that can be used. It participates in various physiological activities such as cellular material metabolism, energy synthesis, and cellular DNA repair.
2. What is NMN?
NMN occurs naturally in living cells and is a precursor to the coenzyme NAD+. Has the effect of prolonging life.
3. Can NMN really fight aging?
NMN is an effective anti-aging substance, and this conclusion has been generally recognized by the scientific community today. Since 2013, hundreds of experimental papers related to NMN have been published in well-known scientific journals such as "Cell", "Nature" and "Science".
4. What is the difference between β-NMN and α-NMN?
NMN is divided into β-NMN and α-NMN. The two look very similar. The only difference is the position of a chemical bond, which leads to different spatial structures and ultimately different biological activities. β-NMN has biological activity, α-NMN has no biological activity, that is to say, it is β-NMN that really works. Regardless of the production process used, both β-NMN and α-NMN are produced in each batch of NMN feedstock. Therefore, the pure high purity of NMN does not mean more effectiveness, but also proves that the high content of β-NMN is really good.
5. Some NMN products on the market claim to be as high as 99.9% pure, is that true?
There are NMNs with a purity of up to 99.9%, but not all NMNs that claim to be high-purity are really high-purity.
6. Is it better to add more NMN raw materials?
Adding a large amount does not mean good quality. Here we need to distinguish two points.
First, is it true that NMN raw materials are added? If it is impersonated by substances with very similar molecular formulas such as NR, NA, NAM, etc., it is meaningless to add a large amount. And a large amount of NA, NAM, etc. will also have side effects.
Second, NMN is divided into β-NMN and α-NMN. The former has biological activity and the latter has no biological activity. If there is no effective inspection report to prove the purity of the raw material and the content of β-NMN, no matter how high the amount of addition is meaningless.
Therefore, whether it is a high content of β-NMN can better explain the quality of the product.
7. Is it safe to take NMN?
In a large number of experiments with NMN, there were no obvious drug-induced side effects. Relevant studies at home and abroad have shown that no side effects have been found when the dose is many times higher than the normal dose.
8. What is the safe dosage of NMN?
In 2016, a team of professors at the University of Washington conducted a long-term experiment on oral NMN in mice. Experiments have found that long-term oral administration of NMN to mice at a dose of 100 mg/kg/d can slow most of the physiological decline associated with aging. The equivalent dose in humans is 8 mg/kg/d, which is equivalent to about 520 mg per day for an adult weighing 65 kg.
Combined with the conclusion that "a single oral dose of 500 mg of NMN is safe" from the NMN clinical study published in 2020, it is recommended that the safe dosage of NMN is about 500 mg per day.
9. How long does it take for NMN to be effective?
The effects of taking NMN vary from person to person, mainly depending on their own state. It takes three or four weeks to experience the effect if you are physically fit and energetic. People with chronic diseases, infirmity, and sub-health will experience rapid and obvious effects, generally within a week.
10. Why is it not recommended to take NMN at night?
After taking NMN, the level of NAD+ in the body increases, and the level of ATP, an energy molecule produced by mitochondria, increases, which will easily cause excessive energy, especially for people with a high degree of excitement at night, which can easily affect sleep.
11. Will eating NMN cause dependence?
According to human experiments, taking NMN will not have physiological dependence. Because NMN is a substance in the human body, it is also contained in many foods. It is not addictive and has no side effects when taken for a long time, so it can be taken with confidence.
12. Are there any side effects of taking NMN for a long time? Does it still work if I stop taking it?
Many natural foods, vegetables and fruits contain NMN, and long-term use has no side effects, so don't worry. Stopping taking NMN will not cause adverse effects on the body, but the improvement brought by NMN will gradually fade over time.
13. Can I eat NMN raw materials directly?
(1) NMN raw materials should not be taken directly. The NMN raw materials on the market are industrial grade or used in experiments. There is a high risk of direct consumption, and raw materials that have not been processed may be contaminated and contain impurities.
(2) Unprocessed NMN raw materials have high acidity, and direct consumption will stimulate the digestive system, which may cause or aggravate digestive system diseases.
14. Can NMN be taken with other health products?
NMN is an innate substance in the human body and will not conflict with common health care products on the market. It is safe to take together. However, there are many kinds of health care products on the market, so it is recommended to take them at an interval of more than 1 hour.
15. Can NMN be taken together with hypoglycemic and antihypertensive drugs?
Studies have shown that long-term use of NMN is helpful for stabilizing blood pressure and improving insulin sensitivity. It is recommended to stagger the taking time of NMN and antihypertensive drugs and hypoglycemic drugs by more than 2 hours. At the same time, monitor blood pressure and blood sugar every day. If there is a decrease, the dosage of the drug can be reduced with the consent of the doctor.
