Lycopene is a fat-soluble functional ingredient with great development prospects and has a variety of physiological activities. However, lycopene has poor processing stability and low bioavailability. At present, most of the domestic and foreign countries use a single macromolecular carrier to construct a delivery system, so as to realize the loading and controlled release of fat-soluble food functional factors. For example, some macromolecular food materials (isolated soy protein, gelatinized corn starch, etc.) are used as carriers to prepare microcapsules, nanoemulsions, and nanoliposomes to embed and load functional ingredients, with the help of these special carrier systems. The transport of active substances in the body.
Wang Qingyu, Wang Mengyao, Chen Lei* of the School of Life Sciences, Anhui University, Anhui Key Laboratory of Ecological Engineering and Biotechnology, and others constructed a pectin/sodium caseinate composite delivery system loaded with lycopene to study the effects of lycopene Addition of lycopene encapsulation efficiency; through Fourier transform infrared spectroscopy (FT-IR), transmission electron microscope (TEM), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) instrument for ternary composite Characterization of lycopene particles, analysis of the particle size distribution, chemical structure and apparent morphology of the complex; construction of in vitro simulated stomach and intestinal digestion models, with embedding rate and loading as indicators, to study the effect of lycopene at different pH values and The release behavior of different concentrations of digestive tract simulation fluid (simulated gastric juice, intestinal juice) was measured to determine the release efficiency of lycopene, and the gastrointestinal controlled release mechanism of lycopene was preliminarily discussed.
Under the condition that the mass ratio of lycopene/binary complex is 10%, the mass ratio of pectin/sodium caseinate is calculated as 10%, 20%, 30%, 40% based on the absorbance of each sample at the wavelength of 471 nm. The embedding rate of lycopene at% is 95.74%, 96.37%, 93.63%, 93.15%, respectively. When the mass ratio of pectin/sodium caseinate is 20%, the embedding rate of lycopene by the binary complex The highest rate.
Construction results of pectin/sodium caseinate composite delivery system
Under the condition that the mass ratio of pectin/sodium caseinate is 20%, the calculation is based on the absorbance of each sample at the wavelength of 471 nm, and the load rate is 4%, 8%, 10%, 12%, 16%. The embedding rate of lycopene by the compound is 85.30%, 96.93%, 93.09%, 79.70%, 84.68%, and the results show that when the loading rate, that is, the lycopene/binary compound is 8%, the binary compound The embedding rate of lycopene is the highest.
