With the improvement of living standards and changes in lifestyle, the incidence of obesity and type 2 diabetes is gradually increasing. Obesity can lead to abnormal glucose metabolism and insulin resistance, which accelerates the occurrence of type 2 diabetes. Type 2 diabetes patients often have abnormal lipid metabolism. Simple control of blood sugar cannot completely eliminate the potential risks of coronary heart disease and other macrovascular complications in diabetic patients. While controlling blood sugar, lipid-lowering treatment must be carried out. At present, the treatment of type 2 diabetes is still limited to symptomatic treatment. Long-term use of hypoglycemic drugs will produce inevitable side effects, and surgical treatment is risky and expensive.
The global epidemic of obesity has promoted the weight-loss drug market to become one of the fastest-growing markets in developed countries. However, safety issues have made the synthetic weight-loss drug market face huge difficulties. Serious adverse events forced most of the synthetic weight-loss drugs to withdraw from the market. Searching for safe and efficient hypoglycemic and lipid-lowering drugs among natural products has become a research hotspot.
Continuous research results show that chlorogenic acid can improve insulin sensitivity and regulate sugar and lipid metabolism, It is of great significance for the prevention and treatment of obesity, diabetes and metabolic syndrome. At present, chlorogenic acid extracted from green coffee beans is widely used in the natural ingredients market.
What is green coffee bean?
Green coffee bean is unroasted coffee, which is naturally green, but normal coffee is usually roasted to turn brown before being sold to consumers. Unroasted coffee beans contain antioxidants and pharmacologically active compounds. The two most important ones are caffeine and chlorogenic acid. Usually, the coffee we drink is roasted without chlorogenic acid. Therefore, chlorogenic acid is considered to be the main active ingredient in green coffee beans, but is pure green coffee extract safe for diabetics?
Green coffee bean extract does contain some caffeine, which can produce weight loss effects. A number of studies have shown that caffeine can promote metabolism by 3-11%. However, the main active ingredient in green coffee is believed to be chlorogenic acid. Some human studies have shown that chlorogenic acid can reduce the absorption of carbohydrates in the digestive tract, thereby reducing blood sugar and insulin peaks. In addition, experimental studies in mice and rats have shown that chlorogenic acid can reduce weight, fat absorbed from the diet, fat stored in the liver, and improve the function of the fat-burning hormone adiponectin. Chlorogenic acid has also been shown to significantly improve cholesterol and triglyceride levels in rats. These are important risk factors for heart disease.
Green coffee bean extract is low in caffeine, so there are few or no side effects related to caffeine intake. Green coffee bean extracts are commercially available in capsule, tablet and powder forms. The dosage of capsules and tablets ranges from 100-500 mg. The powder is often dissolved in hot water and ingested, which is somewhat similar to a cup of instant black coffee. Some medical institutions recommend taking a few capsules or tablets per day, while limiting the dosage. In addition, it is not recommended to take this product with dairy products, because green coffee extract may react with milk.
