How Does Amygdalin Turn Into Cyanide?
Amygdalin, a naturally occurring compound found in apricot kernels and other seeds, can turn into cyanide when metabolized. When amygdalin comes into contact with certain enzymes in the digestive system, such as beta-glucosidase, it breaks down and releases cyanide.
Cyanide is highly toxic, capable of interfering with cellular respiration and potentially fatal in large amounts. Understanding this process and its implications is crucial, especially if you're considering amygdalin as a supplement. Contact us for free samples and more information on safely using amygdalin extract.

How Much Amygdalin is Fatal?
The amount of amygdalin that can become lethal depends on various factors, including a person's body weight and metabolism. When ingested, amygdalin breaks down into glucose, benzaldehyde, and cyanide.
Even though amygdalin is natural, the cyanide it produces is a deadly poison. Ingesting just 0.5 to 3.5 milligrams of cyanide per kilogram of body weight can be fatal. This means that consuming even a small amount of amygdalin-containing seeds like apricot kernels can lead to cyanide poisoning if enough amygdalin is metabolized.
Research suggests that eating around 50 to 60 apricot kernels, depending on size and cyanide content, could result in a fatal dose of cyanide. This is why it is essential to regulate intake and understand the risks involved.
How Much Amygdalin is in One Apricot Kernel?
Apricot kernels are the primary source of amygdalin. The concentration of amygdalin in a single apricot kernel can vary depending on the variety and origin, but typically, one kernel contains about 0.5 to 3 milligrams of amygdalin. This amount can potentially release up to 0.15 to 0.18 milligrams of cyanide when metabolized.
Given the relatively high concentration, consuming a handful of apricot kernels can easily exceed safe cyanide levels. This is especially dangerous when consuming unregulated raw kernels. It's important to always consult a health professional before considering them as part of any diet or supplement routine.
What is the Mechanism of Action of Amygdalin?
Amygdalin's mechanism of action primarily involves its breakdown in the body. Once ingested, the beta-glucosidase enzyme in the small intestine interacts with amygdalin. This interaction causes amygdalin to decompose into cyanide, benzaldehyde, and glucose. The key concern is cyanide, a potent cellular toxin that interferes with the body's ability to use oxygen.
Cyanide blocks the activity of the enzyme cytochrome c oxidase in the mitochondria, inhibiting cellular respiration. This results in tissue hypoxia, especially in vital organs like the heart and brain. This chain reaction is what makes cyanide so dangerous, as it leads to rapid organ failure and death if consumed in large amounts.
While some proponents of amygdalin claim it has therapeutic benefits, particularly in cancer treatment (referred to as laetrile therapy), there is no scientific consensus supporting its efficacy. Moreover, its potential for causing cyanide poisoning is a serious risk.
How Much Cyanide is in 1 Apricot Kernel?
The amount of cyanide that one apricot kernel can produce varies depending on the kernel's amygdalin concentration. On average, one apricot kernel contains between 0.25 to 0.5 milligrams of cyanide. This amount is relatively small, but if multiple kernels are consumed, the cyanide levels can quickly become toxic.
For example, consuming just 5 to 10 apricot kernels can result in cyanide poisoning, with symptoms including nausea, headache, dizziness, and confusion. Higher doses can lead to more severe complications, such as respiratory failure or even death. This is why it's crucial to approach amygdalin consumption with caution.
How Do You Remove Cyanide From Apricot Kernels?
There are several ways to reduce or remove cyanide from apricot kernels, though none guarantee complete safety. Some methods include:
- Soaking and fermenting: Soaking apricot kernels in water or fermenting them can help reduce the amygdalin content. Fermentation activates certain enzymes that help break down amygdalin before it releases cyanide. However, this process may not eliminate all the cyanide.
- Boiling: Heat can also reduce cyanide levels. Boiling apricot kernels at high temperatures can break down amygdalin and reduce its ability to release cyanide. However, studies show that significant amounts of amygdalin may remain intact, leaving a risk of cyanide poisoning.
- Blanching and drying: Some research suggests that blanching or drying apricot kernels can reduce their toxicity, though this method isn't foolproof either.
If you plan to consume apricot kernels or use products derived from them, it's important to consider only those that are properly processed and regulated. Contact us for free samples of our high-quality, carefully processed amygdalin extract to ensure safety and efficacy.
Is Amygdalin Destroyed by Heat?
Yes, amygdalin is somewhat heat-sensitive, and heating apricot kernels can reduce the release of cyanide. Boiling or roasting the kernels at high temperatures can degrade amygdalin, potentially making the kernels safer to consume. However, complete destruction of amygdalin through heat alone is unlikely, and cyanide may still be released when the remaining amygdalin breaks down during digestion.
The effectiveness of heat in reducing amygdalin content depends on both the temperature and duration of the heat exposure. For example, roasting at temperatures above 140°C (284°F) may lower amygdalin levels, but the process needs to be long enough to have a significant effect. Even then, some risk remains.
If you are interested in safer alternatives, consider choosing processed amygdalin extracts, which undergo rigorous testing to ensure minimal cyanide content. Contact us for free samples of our amygdalin extract supplements that meet stringent safety standards.
FAQ
Q:What are the symptoms of cyanide poisoning from amygdalin?
A:Symptoms of cyanide poisoning include headache, dizziness, weakness, nausea, confusion, and difficulty breathing. In severe cases, it can lead to seizures, coma, or death.
Q:Is it safe to consume apricot kernels?
A:In moderate amounts, apricot kernels may be consumed, but they must be treated or processed to reduce amygdalin content. The risk of cyanide poisoning makes unregulated consumption unsafe.
Q:Can amygdalin be used for cancer treatment?
A:There is no reliable scientific evidence supporting the use of amygdalin, or laetrile, as an effective cancer treatment. The risks associated with cyanide poisoning far outweigh any purported benefits.
Q:How can I ensure the amygdalin supplement I take is safe?
A:Look for supplements from reputable manufacturers like KINGSCI, which follow Good Manufacturing Practices (GMP) and offer certified products. Ensure the product has been tested for cyanide content.
For further inquiries about our amygdalin extract or to ensure the safest products available, contact us for free samples. Our high-quality extracts are GMP certified, fast-delivered, and rigorously tested for safety.
References
- McAdam, E., et al. "Cyanogenic Glycosides and Human Health: A Review." Toxicon, vol. 69, 2013, pp. 7-14.
- Holzman, D.C. "Laetrile: The Making of a Myth." Science, vol. 194, no. 4268, 1976, pp. 836-839.
- Bradford, D.A. "Toxicology of Cyanide and its Breakdown Products in Relation to Amygdalin (Laetrile)." JAMA, vol. 244, no. 22, 1980, pp. 2546-2550.






