The times are developing, society is progressing, and people's life is getting faster and faster, which is accompanied by emotional stress and physical fatigue. Studies on improving sleep and relieving physical fatigue have found that lemon balm extract can relieve stress. For many years, lemon balm is a traditional folk medicine widely used as a mild tranquilizer, antispasmodic and antibacterial agent. This plant has a wide range of uses. For example, when encountering insect bites or wounds, fresh lemon balm leaves can be directly applied. It can reduce swelling and relieve pain in the affected area. Lemon balm dry leaves make a medicine pillow to help sleep. And Lemon balm extract can be used as a mild sedative or sedative for anti-anxiety, and it has the function of improving psychological mood.
Rosmarinic acid is one of the effective ingredients of lemon balm. Experiments have shown that it can inhibit GABA transaminase and the degradation of GABA, thereby increasing the concentration of GABA in the brain, playing a sedative, soothing and anti-anxiety effect. In addition, the other two main components of lemon balm extract: caffeic acid and citral have been experimentally proven to have anti-anxiety effects. In the experiment, the animal model of depression induced by unpredictable mild stress (CUMS) was used, and then the sucrose water energy consumption experiment, the opening experiment, and the forced swimming experiment were used to evaluate the depression-like behavior of the animals. The behavioral evaluation found that lemon balm leaf extract can increase the frequency of spontaneous activities in mice
and increase interest in things.
