Hampered by its potent antioxidant properties, astaxanthin, a natural carotenoid present in microalgae, salmon, krill, and shrimp, has been one of the topics of the year lately. As increasing usage by supplement buyers and manufacturers of functional foods increases, there arises concern about the long-term significance and health effects of astaxanthin. One of the dreads of some consumers is whether further exposure to astaxanthin would cause some terrible long-term health conditions.
We will discuss the evidence on the safety of astaxanthin and help demolish some of the myths that surround this ingredient-note that no medical diseases are being proclaimed here.
What Is Astaxanthin?
Astaxanthin is a fat-soluble pigment belonging to the xanthophyll family of carotenoids. Unlike other carotenoids such as beta-carotene or lutein, astaxanthin contains unique molecular structures that allow it to span cell membranes, enabling it to protect both the inner and outer layers from oxidative stress. This makes it a popular ingredient in health supplements for supporting eye, skin, and muscle health.
Natural Sources vs. Synthetic Versions
The main suppliers of astaxanthin are:: Natural microalgae, such as Haematococcus pluvialis, or in lab by chemical syntheses. Extraction of astaxanthin from H. pluvialis is usually appreciated for increased safety and improved bioavailability. As FDA dictates, the use of natural astaxanthin derived from H. pluvialis in dietary supplements at established limits is considered GRAS.
Regulatory Status and Safety Reviews
A number of large regulatory authorities have made comprehensive assessments of the safety of astaxanthin.
EFSA (European Food Safety Authority): Performed safety testing which established that astaxanthin can be consumed safely in quantities up to 0.034mg/kg body weight per day.
United States Food and Drug Administration (FDA): Granted natural astaxanthin to have GRAS status, allowing its utilization in different food and supplements contexts.
Japan's FOSHU: Confirms the positive health promoting effects ascribed to astaxanthin in foods for health use.
The safety profile results from reliable data corresponding to toxicological evaluation, analysis on how astaxanthin is metabolized, as well as human clinical experiences, which prove it is safe to be consumed at recommended doses.
Human Clinical Studies and Observations
In the past ten years, many health benefits of astaxanthin supplementation in various health areas have been explored in double-blind, placebo-controlled clinical studies. Such trials are usually visited by participants taking between 2 mg and 12 mg of astaxanthin daily, and effects observed include those affecting oxidative stress, skin conditions, and exercise capacity. The trials showed no great adverse effects.
Additionally, findings show that the astaxanthin stays stable in the body, exhibiting proper uptake when combined with fats-loaded foods. There is also no proof for astaxanthin buildup to unsafe levels within our bodies.
FAQ
Q1: Is there no problem with long-term use of astaxanthin?
Yes. The extended use of astaxanthin, within several months, seems to be safe, and it is backed by studies in case it is used as instructed.
Q2: Can astaxanthin be taken daily?
Topping up a daily intake with quantities between 4 and 8 mg is deemed safe and normal for fit people.
Q3: Does astaxanthin interfere with medications?
Although there is no evidence of major drug interactions, it would be wise to consult your doctor in regards to the use, especially if you are taking anticoagulants or immune-modulating drugs.
Q4: Is there no mature research record on the use of astaxanthin by pregnant and breastfeeding women?
There is little research on these groups of people. Consult a healthcare professional, before starting any astaxanthin supplement.
Positive results and a favorable safety profile seem to be associated with astaxanthin consumption, responsible and moderate. There is a predisposition for misinformation to promote anxiety, but there is clear scientific research and safety reviews that support its incorporation into wellness products safely. Interested product formulators, distributors, or buyers for high-quality astaxanthin ingredients can reach out to us at donna@kingsci.com for other technical data, pricing, and customized.
References
- EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). (2014). Scientific Opinion on the safety of astaxanthin-rich oleoresin from Haematococcus pluvialis as a novel food ingredient. EFSA Journal, 12(7), 3757. https://doi.org/10.2903/j.efsa.2014.3757
- Fassett, R. G., & Coombes, J. S. (2012). Astaxanthin: A potential therapeutic agent in cardiovascular disease. Marine Drugs, 10(11), 2546–2560. https://doi.org/10.3390/md10112546
- Kidd, P. (2011). Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Alternative Medicine Review, 16(4), 355–364.
- Ambati, R. R., Phang, S. M., Ravi, S., & Aswathanarayana, R. G. (2014). Astaxanthin: Sources, extraction, stability, biological activities and its commercial applications-A review. Marine Drugs, 12(1), 128–152. https://doi.org/10.3390/md12010128
- Guerin, M., Huntley, M. E., & Olaizola, M. (2003). Haematococcus astaxanthin: Applications for human health and nutrition. Trends in Biotechnology, 21(5), 210–216. https://doi.org/10.1016/S0167-7799(03)00078-7
